넥스트앤바이오의 췌장암 환자 유래 오가노이드를 통한 항암제 감수성 평가기술이 국보건의료연구원(NECA)으로부터 혁신의료기술로 선정됐다. 사진은 양지훈 넥스트앤바이오 공동대표. /사진=넥스트앤바이오 넥스트앤바이오가 오가노이드를 활용해 췌장암 환자에 맞는 항암제를 선별하는 기술을 상용화할 전망이다. '인공장기'로 불리는 오가노이드는 사람 줄기세포에 기반한 인공장기 유사체로 인체 특정 장기에 작용하는 치료제의 효능을 직접 확인할 수 있어 신약 개발 성공 가능성을 높일 수 있는 기술로 주목받고 있다.넥스트앤바이오는 최근 한국보건의료연구원(NECA)으로부터 췌장암 환자 유래 오가노이드를 통한 항암제 감수성 평가기술이 혁신의료기술로 선정됐다고 31일 밝혔다. 항암치료제 사용에 앞서 항암제에 대한 감수성 여부를 확인해 최적의 약물 선택을 보조하는 데 잠재성이 높고 안전하다는 평가를 받으며 오가노이드 기반 의료기술 중 최초로 혁신의료기술로 인정받은 것이다.넥스트앤바이오의 오가노이드 기반 췌장암 항암제 감수성 검사 기술은 세침 생검 바늘(FNB)로 췌장암 환자의 세포조직을 극소량 채취해 오가노이드로 배양한 이후 이를 통해 항암제별 민감도를 확인하는 검사다. 췌장암은 바이오마커(생체표지) 등 환자에게 최적화된 항암제를 선택하는 데 있어 명확한 기준이 없는 것으로 알려졌다.췌장암 오가노이드 기반의 항암제 감수성 평가 검사를 통해 환자들은 최소 침습 조직검사만으로 본인에게 맞는 최적의 약물을 선택할 수 있을 것으로 예상된다.혁신의료기술로 선정되면 보건복지부 고시 및 실시기관 사용 신고 후 임상에서 선별급여 또는 비급여 형태로 즉시 사용할 수 있어 넥스트앤바이오의 췌장암 오가노이드 기반 항암제 감수성 평가기술도 국내 의료현장에서 사용할 수 있게 됐다.양지훈 넥스트앤바이오 공동대표는 "이번 혁신의료기술 승인은 오가노이드가 임상현장에서 본격적으로 사용될 수 있게 됐고 치료가 까다롭고 예후가 좋지 않은 췌장암 환자에게 최적의 항암제를 선택할 수 있는 길이 열렸다는 점에서 큰 의미를 가진다"고 말했다.
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