투자자 궁금한 질문 종합 정리내년 임상 1상 진입 예정천연물 신약 특성인, 흡수, 분포, 대사, 배출 등 증빙은 과제이 기사는 2023년07월31일 09시05분에 팜이데일리 프리미엄 콘텐츠로 선공개 되었습니다.[이데일리 김지완 기자] 투자자들이 궁금해하는 비엘(142760)에 대한 질문 9가지. 이도영 비엘 연구개발본부장(상무, 이학박사) 및 회사 관계자들의 즉답을 정리했다.

이도영 비엘 연구개발본부장(상무, 이학박사)이 2023년 7월 용인 수지 본사에서 이데일리와 인터뷰 중이다. (사진=김지완 기자)-폴리감마글루탄산(γ-PGA)의 효과는 무엇인가.△면역항암제를 투약해 암세포의 PD-L1과 T세포의 PD-1이 결합하지 못하게 만든다. PD-1과 PD-L1이 결합하면 T세포는 자폭 스위치를 켜고 사멸한다. 결과적으로 면역항암제는 T세포 생존을 돕는 역할을 하는 것이다. 문제는 면역항암제를 투여해 T세포를 남겨놨는데, 그 T세포가 비실비실하다면 어떻게 되겠는가. 면역항암제가 T세포 자살 스위치 작동을 막아 면역 세포들을 살려놔도 암세포를 죽일 수 없게 된다. 이런 상황을 ‘이뮨 콜드’(Immune cold)라고 한다. 반대로 면역항암제가 잘 작동하는 게 흑색종, 비소세포폐암 등이 있다. 이런 암들을 가리켜 이뮨 핫(Immune hot)이라고 한다.이뮨 콜드의 대표적인 암종이 간암, 췌장암 등이다. 이런 암종에선 면역항암제 단독 투여는 효과가 미미하다. 연구자들은 여기서 면역 세포 활성을 높여주고, 숫자를 늘려주면 면역항암제가 잘 작동할 수 있다고 판단했다. 폴리감마글루탄산을 면역항암제 병용치료제로 개발하는 이유다. 폴리감마글루탄산은 이뮨 콜드를 핫으로 바꾸는 역할을 굉장히 잘 할 수 있다.-구체적으로 효과를 얼마나 기대할 수 있나.△폴리감마글루탐산의 서울성모병원에서 수행된 인체적용시험에서 8주 복용 시 NK(자연살해)세포 활성이 52.3% 증가했다. -면역항암제가 잘 작동하는 암종에선 병용 요법이 필요없단 얘긴가.△면역항암제 효능을 높여준다는 측면에서 보면 폴리감마글루탐산+면역항암제 병용요법은 모든 암종에서 효과가 있을 것으로 기대된다.
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<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">이천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">구리 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">안성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">포천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">의왕 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">여주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">동두천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">가평 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">과천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">연천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">강원도 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">횡성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영월 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">정선 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">화천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">양구 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">인제 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">양양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">원주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">홍천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">평창 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">철원 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">고성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">춘천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">강릉 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">동해 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">태백 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">속초 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">삼척 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">충남 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">부여 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">홍성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">예산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">아산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">금산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">서천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">청양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">태안 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">당진 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">공주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">보령 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">서산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">논산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">계룡 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">충북 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">증평 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">괴산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">음성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">단양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">충주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">제천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">보은 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">옥천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영동 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">진천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">전남 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">담양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">곡성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">구례 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">고흥 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">장흥 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">강진 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">해남 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영암 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">무안 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">함평 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영광 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">장성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">완도 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">진도 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">신안 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">여수 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">목포 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">보성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">화순 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">나주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">순천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">광양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">전북 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">진안 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">장수 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">임실 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">순창 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">고창 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">부안 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">익산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">군산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">정읍 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">김제 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">무주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">남원 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">완주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">경남 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">밀양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">의령 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">함안 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">창녕 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">남해 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">하동 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">산청 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">함양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">거창 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">합천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">김해 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">거제 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">진주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">통영 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">사천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">양산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">경북 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">군위 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">의성 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">청송 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영양 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영덕 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">청도 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">고령 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">성주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">칠곡 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">예천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">봉화 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">울진 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">울릉 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">포항 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">영천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">경주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">김천 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">안동 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">구미 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">상주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">문경 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">경산 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">세종 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">전주 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">완산구 엘레베이터</a>
<a href="https://dahaeyo.co.kr/elevator" target="_blank" rel="noreferrer noopener">덕진구 엘레베이터</a>